5-BROMO-IMIDAZO[1,2-A]PYRIDINE
5-Bromoimidazo[1,2-a]pyridine
CAS: 69214-09-1
Molecular Formula: C7H5BrN2
5-BROMO-IMIDAZO[1,2-A]PYRIDINE - Names and Identifiers
| Name | 5-Bromoimidazo[1,2-a]pyridine |
| Synonyms | 5-Bromoimidazo[1,2-a]pyridine 5-Bromo-Imidazo[1,2-A]Pyridine 5-BROMO-IMIDAZO[1,2-A]PYRIDINE 5-bromoH-imidazo[1,2-a]pyridine Imidazo[1,2-a]pyridine, 5-bromo- 5-BROMO-5H-IMIDAZO[2,1-B][1,3]OXAZINE 5-Bromo-1,5-dihydroimidazo[1,2-a]pyridine |
| CAS | 69214-09-1 |
| EINECS | 1592732-453-0 |
| InChI | InChI=1/C7H5BrN2/c8-6-2-1-3-7-9-4-5-10(6)7/h1-5H |
5-BROMO-IMIDAZO[1,2-A]PYRIDINE - Physico-chemical Properties
| Molecular Formula | C7H5BrN2 |
| Molar Mass | 197.03 |
| Density | 1.69±0.1 g/cm3(Predicted) |
| Melting Point | 61-64℃ |
| Solubility | Chloroform (Slightly), DMSO (Slightly) |
| Appearance | Solid |
| Color | Pale Brown to Light Brown |
| pKa | 5.15±0.50(Predicted) |
| Storage Condition | Keep in dark place,Sealed in dry,Room Temperature |
| Refractive Index | 1.688 |
5-BROMO-IMIDAZO[1,2-A]PYRIDINE - Risk and Safety
| WGK Germany | 3 |
5-BROMO-IMIDAZO[1,2-A]PYRIDINE - Introduction
5-Bromoimidazo[1,2-a]pyridine is an organic compound with the chemical formula C6H4BrN3. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
-Appearance: Colorless to light yellow crystalline powder.
-Melting point: about 110-111 ℃.
-Solubility: Soluble in most organic solvents, such as dimethyl sulfoxide and dichloromethane.
-Stability: Stable at room temperature, but may decompose under light conditions.
Use:
5-Bromoimidazo[1,2-a]pyridine is an important organic synthesis intermediate, which is widely used in the fields of medicine and pesticide. It can be used to synthesize a variety of biologically active compounds, such as drug molecules, pesticides and chemical sensors.
Preparation Method:
5-Bromoimidazo[1,2-a]pyridine is prepared mainly by the reaction between chloroformic acid and imidazole. First, chloroformic acid and imidazole are heated and reacted in an appropriate solvent. During the reaction, chloroformate will be generated and participate in the cyclization reaction, and finally the target product 5-Bromoimidazo[1,2-a]pyridine is obtained.
Safety Information:
5-Bromoimidazo[1,2-a]pyridine is less toxic, but safe handling should be considered. Personal protective equipment, such as laboratory gloves and protective glasses, should be worn during operation. Avoid contact with skin and inhalation of dust. If ingested or inhaled, seek medical attention immediately.
Nature:
-Appearance: Colorless to light yellow crystalline powder.
-Melting point: about 110-111 ℃.
-Solubility: Soluble in most organic solvents, such as dimethyl sulfoxide and dichloromethane.
-Stability: Stable at room temperature, but may decompose under light conditions.
Use:
5-Bromoimidazo[1,2-a]pyridine is an important organic synthesis intermediate, which is widely used in the fields of medicine and pesticide. It can be used to synthesize a variety of biologically active compounds, such as drug molecules, pesticides and chemical sensors.
Preparation Method:
5-Bromoimidazo[1,2-a]pyridine is prepared mainly by the reaction between chloroformic acid and imidazole. First, chloroformic acid and imidazole are heated and reacted in an appropriate solvent. During the reaction, chloroformate will be generated and participate in the cyclization reaction, and finally the target product 5-Bromoimidazo[1,2-a]pyridine is obtained.
Safety Information:
5-Bromoimidazo[1,2-a]pyridine is less toxic, but safe handling should be considered. Personal protective equipment, such as laboratory gloves and protective glasses, should be worn during operation. Avoid contact with skin and inhalation of dust. If ingested or inhaled, seek medical attention immediately.
Last Update：2024-04-09 02:00:47
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